Distinct Neurotoxicity Profile of Listeriolysin O from Listeria monocytogenes

Cholesterol-dependent cytolysins (CDCs) are protein toxins that originate from Gram-positive bacteria and contribute substantially to their pathogenicity. CDCs bind membrane cholesterol and build prepores and lytic pores. Some effects of the toxins are observed in non-lytic concentrations. Two patho...

Full description

Bibliographic Details
Main Authors: Jana Maurer, Sabrina Hupp, Carolin Bischoff, Christina Foertsch, Timothy J. Mitchell, Trinad Chakraborty, Asparouh I. Iliev
Format: Article
Language:English
Published: MDPI AG 2017-01-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/9/1/34