Inhaled steroids modulate extracellular matrix composition in bronchial biopsies of COPD patients: a randomized, controlled trial.

Inhaled steroids modulate extracellular matrix composition in bronchial biopsies of COPD patients: a randomized, controlled trial.

Smoking and inflammation contribute to the pathogenesis of chronic obstructive pulmonary disease (COPD), which involves changes in extracellular matrix. This is thought to contribute to airway remodeling and airflow obstruction. We have previously observed that long-term treatment with inhaled corti...

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Bibliographic Details
Main Authors: Lisette I Z Kunz, Jolanda Strebus, Simona E Budulac, Therese S Lapperre, Peter J Sterk, Dirkje S Postma, Thais Mauad, Wim Timens, Pieter S Hiemstra, GLUCOLD (Groningen Leiden Universities Corticosteroids in Obstructive Lung Disease) Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3646783?pdf=render

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http://europepmc.org/articles/PMC3646783?pdf=render

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