Isatin Counteracts Diethylnitrosamine/2-Acetylaminofluorene-Induced Hepatocarcinogenesis in Male Wistar Rats by Upregulating Anti-Inflammatory, Antioxidant, and Detoxification Pathways

Isatin Counteracts Diethylnitrosamine/2-Acetylaminofluorene-Induced Hepatocarcinogenesis in Male Wistar Rats by Upregulating Anti-Inflammatory, Antioxidant, and Detoxification Pathways

Hepatocellular carcinoma (HCC) represents around 85% of all known types of liver cancers and is estimated to be the fifth most common cause of cancer-related death worldwide. The current study assessed the preventive efficacy of isatin on diethylnitrosamine (DENA)/2-acetylaminofluorene (2-AAF)-induc...

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Bibliographic Details
Main Authors: Nagwa G. Tawfik, Wafaa R. Mohamed, Hanan S. Mahmoud, Mohammed A. Alqarni, Ibrahim A. Naguib, Alzhraa M. Fahmy, Osama M. Ahmed
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Antioxidants
Subjects:
hepatocellular carcinoma
diethylnitrosamine
acetylaminofluorene
isatin
inflammation
apoptosis
Online Access:https://www.mdpi.com/2076-3921/11/4/699

Internet

https://www.mdpi.com/2076-3921/11/4/699

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