Neoadjuvant multidrug chemotherapy including High-Dose Methotrexate modifies VEGF expression in Osteosarcoma: an immunohistochemical analysis

Neoadjuvant multidrug chemotherapy including High-Dose Methotrexate modifies VEGF expression in Osteosarcoma: an immunohistochemical analysis

<p>Abstract</p> <p>Background</p> <p>Angiogenesis plays a role in the progression of osteosarcoma, as well as in other mesenchymal tumors and carcinomas, and it is most commonly assessed by vascular endothelial growth factor (VEGF) expression or tumor CD31-positive micr...

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Bibliographic Details
Main Authors: Rosa Michele A, Signorelli Diego, Scaramuzzo Laura, Maccauro Giulio, Schinzari Giovanni, Rossi Barbara, Fabbriciani Carlo, Carlo Barone
Format: Article
Language:English
Published: BMC 2010-02-01
Series:BMC Musculoskeletal Disorders
Online Access:http://www.biomedcentral.com/1471-2474/11/34

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http://www.biomedcentral.com/1471-2474/11/34

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