Inflammatory Drivers of Cardiovascular Disease: Molecular Characterization of Senescent Coronary Vascular Smooth Muscle Cells

The senescence of vascular smooth muscle cells (VSMCs) has been implicated as a causal pro-inflammatory mechanism for cardiovascular disease development and progression of atherosclerosis, the instigator of ischemic heart disease. Contemporary limitations related to studying this cellular population...

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Bibliographic Details
Main Authors: Stevan D. Stojanović, Maximilian Fuchs, Meik Kunz, Ke Xiao, Annette Just, Andreas Pich, Johann Bauersachs, Jan Fiedler, Daniel Sedding, Thomas Thum
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00520/full