Modeling chemotaxis reveals the role of reversed phosphotransfer and a bi-functional kinase-phosphatase.
Understanding how multiple signals are integrated in living cells to produce a balanced response is a major challenge in biology. Two-component signal transduction pathways, such as bacterial chemotaxis, comprise histidine protein kinases (HPKs) and response regulators (RRs). These are used to sense...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-08-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC2924250?pdf=render |