Adamtsl3 mediates DCC signaling to selectively promote GABAergic synapse function

Adamtsl3 mediates DCC signaling to selectively promote GABAergic synapse function

Summary: The molecular code that controls synapse formation and maintenance in vivo has remained quite sparse. Here, we identify that the secreted protein Adamtsl3 functions as critical hippocampal synapse organizer acting through the transmembrane receptor DCC (deleted in colorectal cancer). Tradit...

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Bibliographic Details
Main Authors: Teresa M.L. Cramer, Berangere Pinan-Lucarre, Anna Cavaccini, Angeliki Damilou, Yuan-Chen Tsai, Musadiq A. Bhat, Patrizia Panzanelli, Nicolas Rama, Patrick Mehlen, Dietmar Benke, Theofanis Karayannis, Jean-Louis Bessereau, Shiva K. Tyagarajan
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Cell Reports
Subjects:
CP: Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723009580

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http://www.sciencedirect.com/science/article/pii/S2211124723009580

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