Kidney Mass Reduction Leads to l‐Arginine Metabolism‐Dependent Blood Pressure Increase in Mice

Kidney Mass Reduction Leads to l‐Arginine Metabolism‐Dependent Blood Pressure Increase in Mice

BackgroundUninephrectomy (UNX) is performed for various reasons, including kidney cancer or donation. Kidneys being the main site of l‐arginine production in the body, we tested whether UNX mediated kidney mass reduction impacts l‐arginine metabolism and thereby nitric oxide production and blood pre...

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Bibliographic Details
Main Authors: Samyuktha Muralidharan Pillai, Petra Seebeck, Ralph Fingerhut, Ji Huang, Xiu‐Fen Ming, Zhihong Yang, François Verrey
Format: Article
Language:English
Published: Wiley 2018-03-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
arginine
arginine metabolism
blood pressure
kidney
l‐citrulline
sex differences
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.117.008025

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.117.008025

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