NF-κB Signaling and Inflammation—Drug Repurposing to Treat Inflammatory Disorders?

NF-κB is a central mediator of inflammation, response to DNA damage and oxidative stress. As a result of its central role in so many important cellular processes, NF-κB dysregulation has been implicated in the pathology of important human diseases. NF-κB activation causes inappropriate inflammatory...

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Bibliographic Details
Main Authors: Annabell Roberti, Laura Elizabeth Chaffey, David R. Greaves
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/11/3/372