Mutational landscape of gastric cancer and clinical application of genomic profiling based on target next-generation sequencing

Mutational landscape of gastric cancer and clinical application of genomic profiling based on target next-generation sequencing

Abstract Background Gastric cancer (GC) is a leading cause of cancer deaths, and an increased number of GC patients adopt to next-generation sequencing (NGS) to identify tumor genomic alterations for precision medicine. Methods In this study, we established a hybridization capture-based NGS panel in...

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Bibliographic Details
Main Authors: Hui Cai, Changqing Jing, Xusheng Chang, Dan Ding, Ting Han, Junchi Yang, Zhengmao Lu, Xuguang Hu, Zhaorui Liu, Jinshen Wang, Liang Shang, Shouxin Wu, Peng Meng, Ling Lin, Jiangman Zhao, Mingming Nie, Kai Yin
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Journal of Translational Medicine
Subjects:
Gastric cancer
Next-generation sequencing
Tumor mutation burden
Clinical actionable alterations
Online Access:http://link.springer.com/article/10.1186/s12967-019-1941-0

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http://link.springer.com/article/10.1186/s12967-019-1941-0

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