Ketogenic diet containing medium-chain triglyceride ameliorates transcriptome disruption in skeletal muscles of rat models of duchenne muscular dystrophy

Ketogenic diet containing medium-chain triglyceride ameliorates transcriptome disruption in skeletal muscles of rat models of duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is a myopathy characterized by progressive muscle weakness caused by a mutation in the dystrophin gene on the X chromosome. We recently showed that a medium-chain triglyceride-containing ketogenic diet (MCTKD) improves skeletal muscle myopathy in a CRISPR/Cas9 gene-...

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Bibliographic Details
Main Authors: Yuri Fujikura, Keitaro Yamanouchi, Hidetoshi Sugihara, Masaki Hatakeyama, Tomoki Abe, Satoru Ato, Katsutaka Oishi
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Biochemistry and Biophysics Reports
Subjects:
Duchenne muscular dystrophy
Ketogenic diet
Transcriptome
Ketone bodies
Skeletal muscle
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580822001789

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http://www.sciencedirect.com/science/article/pii/S2405580822001789

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