P-Type ATPase Apt1 of the Fungal Pathogen <i>Cryptococcus neoformans</i> Is a Lipid Flippase of Broad Substrate Specificity

P-Type ATPase Apt1 of the Fungal Pathogen <i>Cryptococcus neoformans</i> Is a Lipid Flippase of Broad Substrate Specificity

Lipid flippases of the P4-ATPase family are ATP-driven transporters that translocate lipids from the exoplasmic to the cytosolic leaflet of biological membranes. In the encapsulated fungal pathogen <i>Cryptococcus neoformans</i>, the P4-ATPase Apt1p is an important regulator of polysacch...

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Bibliographic Details
Main Authors: Lyubomir Dimitrov Stanchev, Juliana Rizzo, Rebecca Peschel, Lilli A. Pazurek, Lasse Bredegaard, Sarina Veit, Sabine Laerbusch, Marcio L. Rodrigues, Rosa L. López-Marqués, Thomas Günther Pomorski
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Journal of Fungi
Subjects:
β-subunit
CDC50 protein
heterologous expression
lipid transport
membrane transport protein
P4-ATPase
Online Access:https://www.mdpi.com/2309-608X/7/10/843

Internet

https://www.mdpi.com/2309-608X/7/10/843

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