Neuronal loss of TRPM8 leads to obesity and glucose intolerance in male mice

Neuronal loss of TRPM8 leads to obesity and glucose intolerance in male mice

Objective: Mice with global deletion of the transient receptor potential channel melastatin family member 8 (TRPM8) are obese, and treatment of diet-induced obese (DIO) mice with TRPM8 agonists decrease body weight. Whether TRPM8 signaling regulates energy metabolism via central or peripheral effect...

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Bibliographic Details
Main Authors: D. Liskiewicz, Q. Zhang, C.S. Barthem, M. Jastroch, A. Liskiewicz, N. Khajavi, G. Grandl, C. Coupland, M. Kleinert, C. Garcia-Caceres, A. Novikoff, G. Maity, U. Boehm, M.H. Tschöp, T.D. Müller
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Molecular Metabolism
Subjects:
Obesity
TRPM8
Icilin
BAT
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877823000480

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http://www.sciencedirect.com/science/article/pii/S2212877823000480

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