In vivo solid tumor targeting with recombinant VEGF-diphtheria immunotoxin

In vivo solid tumor targeting with recombinant VEGF-diphtheria immunotoxin

Objective(s): A variety of signaling molecules have been identified that play a role in angiogenesis, of prime importance, vascular endothelial growth factor (VEGF) and its resceptor (VEGFR), which is highly expressed in most human solid tumors. Targeting VEGF or/and VEGFR with immunotoxin may be a...

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Bibliographic Details
Main Authors: Mohammad Hosseininejad-Chafi, Ehsan Alirahimi, Behzad Ramezani, Akbar Oghalaei, Nazli Sotoudeh, Hajarsadat Ghaderi, Fatemeh Kazemi-Lomedasht, Mahdi Habibi-Anbouhi, Reza Moazzami, Mahdi Behdani
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2022-01-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
angiogenesis
immunotherapy
immunotoxin
tumor
vascular endothelial growth - factor (vegf)
Online Access:https://ijbms.mums.ac.ir/article_19108_6007af86ddcf194520f441d519302e32.pdf

Internet

https://ijbms.mums.ac.ir/article_19108_6007af86ddcf194520f441d519302e32.pdf

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