Animal experimental investigation on the efficacy of antibiotic therapy with linezolid, vancomycin, cotrimoxazole, and rifampin in treatment of periprosthetic knee joint infections by MRSA

Animal experimental investigation on the efficacy of antibiotic therapy with linezolid, vancomycin, cotrimoxazole, and rifampin in treatment of periprosthetic knee joint infections by MRSA

Aims Periprosthetic joint infections (PJIs) are rare, but represent a great burden for the patient. In addition, the incidence of methicillin-resistant Staphylococcus aureus (MRSA) is increasing. The aim of this rat experiment was therefore to compare the antibiotics commonly used in the treatment o...

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Bibliographic Details
Main Authors: Julia Goetz, Verena Keyssner, Frank Hanses, Felix Greimel, Franziska Leiß, Timo Schwarz, Hans-Robert Springorum, Joachim Grifka, Jens Schaumburger
Format: Article
Language:English
Published: The British Editorial Society of Bone & Joint Surgery 2022-03-01
Series:Bone & Joint Research
Subjects:
MRSA
Infection of the artificial joint
Combination antibiotics therapies
Antibiotics monotherapy
Vancomycin
Rifampin or cotrimoxazole
Online Access:https://online.boneandjoint.org.uk/doi/10.1302/2046-3758.113.BJR-2021-0268.R1

Internet

https://online.boneandjoint.org.uk/doi/10.1302/2046-3758.113.BJR-2021-0268.R1

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