Lipid Storage and Interferon Response Determine the Phenotype of Ground Glass Hepatocytes in Mice and HumansSummary

Background and Aims: A histopathological hallmark of chronic hepatitis B virus (HBV) infection is the presence of ground glass hepatocytes (GGHs). GGHs are liver cells that exhibit eosinophilic, granular, glassy cytoplasm in light microscopy and are characterized by accumulation of HBV surface (HBs)...

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Main Authors: Yuri Churin, Karuna Irungbam, Christoph S. Imiela, David Schwarz, Hans-Joachim Mollenkopf, Uta Drebber, Margarete Odenthal, Oleg Pak, Magdalena Huber, Dieter Glebe, Martin Roderfeld, Elke Roeb
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X21000618