Human Macrophages Exhibit GM-CSF Dependent Restriction of Mycobacterium tuberculosis Infection via Regulating Their Self-Survival, Differentiation and Metabolism

Human Macrophages Exhibit GM-CSF Dependent Restriction of Mycobacterium tuberculosis Infection via Regulating Their Self-Survival, Differentiation and Metabolism

GM-CSF is an important cytokine that regulates the proliferation of monocytes/macrophages and its various functions during health and disease. Although growing evidences support the notion that GM-CSF could play a major role in immunity against tuberculosis (TB) infection, the mechanism of GM-CSF me...

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Bibliographic Details
Main Authors: Abhishek Mishra, Vipul K. Singh, Chinnaswamy Jagannath, Selvakumar Subbian, Blanca I. Restrepo, Marie-Claire Gauduin, Arshad Khan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Immunology
Subjects:
macrophages
Mycobacterium tuberculosis
tuberculosis
granulocyte macrophage colony-stimulating factor
cell death
antigen presentation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.859116/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.859116/full

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