KSHV-encoded LANA bypasses transcriptional block through the stabilization of RNA Pol II in hypoxia

KSHV-encoded LANA bypasses transcriptional block through the stabilization of RNA Pol II in hypoxia

ABSTRACTHypoxia results from an insufficient supply of oxygen, which results in physiological stress in biological systems. Cells respond to this unfavorable condition by reducing critical cellular functions, which include replication, transcription, and translation. Oncogenic Kaposi sarcoma-associa...

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Bibliographic Details
Main Authors: Dipayan Bose, Rajnish Kumar Singh, Erle S. Robertson
Format: Article
Language:English
Published: American Society for Microbiology 2024-01-01
Series:mBio
Subjects:
hypoxia
KSHV
lytic reactivation
RNA Polymerase II
ubiquitination
Online Access:https://journals.asm.org/doi/10.1128/mbio.02774-23

Internet

https://journals.asm.org/doi/10.1128/mbio.02774-23

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