PM2.5 induce lifespan reduction, insulin/IGF-1 signaling pathway disruption and lipid metabolism disorder in Caenorhabditis elegans

PM2.5 induce lifespan reduction, insulin/IGF-1 signaling pathway disruption and lipid metabolism disorder in Caenorhabditis elegans

IntroductionExposure to fine particulate matter (PM), especially PM2.5, can induce various adverse health effects in populations, including diseases and premature death, but the mechanism of its toxicity is largely unknown.MethodsWater-soluble components of PM2.5 (WS-PM2.5) were collected in the nor...

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Bibliographic Details
Main Authors: Wenjing Zhang, Zinan Li, Guojun Li, Ling Kong, Haiming Jing, Nan Zhang, Junyu Ning, Shan Gao, Yong Zhang, Xinyu Wang, Jing Tao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Public Health
Subjects:
PM2.5
Caenorhabditis elegans
lifespan
healthspan
RNA-Sequencing
gene homology
Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2023.1055175/full

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https://www.frontiersin.org/articles/10.3389/fpubh.2023.1055175/full

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