Dectin-2-dependent NKT cell activation and serotype-specific antibody production in mice immunized with pneumococcal polysaccharide vaccine.

Dectin-2-dependent NKT cell activation and serotype-specific antibody production in mice immunized with pneumococcal polysaccharide vaccine.

Although thymus-independent type 2 antigens generally do not undergo Ig class switching from IgM to IgG, pneumococcal polysaccharide vaccine (PPV) induces the production of serotype-specific IgG. How this happens remains unclear, however. In the present study, PPV immunization induced production of...

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Bibliographic Details
Main Authors: Tomomitsu Miyasaka, Yukiko Akahori, Masahiko Toyama, Namiko Miyamura, Keiko Ishii, Shinobu Saijo, Yoichiro Iwakura, Yuki Kinjo, Yoshitsugu Miyazaki, Kazunori Oishi, Kazuyoshi Kawakami
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3808275?pdf=render

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http://europepmc.org/articles/PMC3808275?pdf=render

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