Parainfluenza Virus 5 V Protein Blocks Interferon Gamma-Mediated Upregulation of NK Cell Inhibitory Ligands and Improves NK Cell Killing of Neuroblastoma Cells

Parainfluenza Virus 5 V Protein Blocks Interferon Gamma-Mediated Upregulation of NK Cell Inhibitory Ligands and Improves NK Cell Killing of Neuroblastoma Cells

Natural killer (NK) cells can be effective immunotherapeutic anti-cancer agents due to their ability to selectively target and kill tumor cells. This activity is modulated by the interaction of NK cell receptors with inhibitory ligands on the surface of target cells. NK cell inhibitory ligands can b...

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Bibliographic Details
Main Authors: Elisabeth M. Shiffer, Jeremiah L. Oyer, Alicja J. Copik, Griffith D. Parks
Format: Article
Language:English
Published: MDPI AG 2024-08-01
Series:Viruses
Subjects:
natural killer cells
parainfluenza virus type 5
immunotherapeutic
interferon-gamma
Online Access:https://www.mdpi.com/1999-4915/16/8/1270

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https://www.mdpi.com/1999-4915/16/8/1270

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