Investigating the potential anti-depressive mechanisms of statins: a transcriptomic and Mendelian randomization analysis
Abstract Observational studies and randomized controlled trials presented inconsistent findings on the effects of cholesterol-lowering statins on depression. It therefore remains unclear whether statins have any beneficial effects on depression, and if so, what the underlying molecular mechanisms ar...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-04-01
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Series: | Translational Psychiatry |
Online Access: | https://doi.org/10.1038/s41398-023-02403-8 |