Transmission phenotype of Mycobacterium tuberculosis strains is mechanistically linked to induction of distinct pulmonary pathology.

In a study of household contacts (HHC), households were categorized into High (HT) and Low (LT) transmission groups based on the proportion of HHC with a positive tuberculin skin test. The Mycobacterium tuberculosis (Mtb) strains from HT and LT index cases of the households were designated Mtb-HT an...

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Main Authors: Sheetal Verma, Kamlesh Bhatt, Arianne Lovey, Rodrigo Ribeiro-Rodrigues, Joan Durbin, Edward C Jones-López, Moises Palaci, Solange A Vinhas, David Alland, Reynaldo Dietze, Jerrold J Ellner, Padmini Salgame
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-03-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007613