Transmission phenotype of Mycobacterium tuberculosis strains is mechanistically linked to induction of distinct pulmonary pathology.

Transmission phenotype of Mycobacterium tuberculosis strains is mechanistically linked to induction of distinct pulmonary pathology.

In a study of household contacts (HHC), households were categorized into High (HT) and Low (LT) transmission groups based on the proportion of HHC with a positive tuberculin skin test. The Mycobacterium tuberculosis (Mtb) strains from HT and LT index cases of the households were designated Mtb-HT an...

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Main Authors: Sheetal Verma, Kamlesh Bhatt, Arianne Lovey, Rodrigo Ribeiro-Rodrigues, Joan Durbin, Edward C Jones-López, Moises Palaci, Solange A Vinhas, David Alland, Reynaldo Dietze, Jerrold J Ellner, Padmini Salgame
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-03-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007613

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