Maternal transfer of florfenicol impacts development and disrupts metabolic pathways in F1 offspring zebrafish by destroying mitochondria

Maternal transfer of florfenicol impacts development and disrupts metabolic pathways in F1 offspring zebrafish by destroying mitochondria

Maternal exposure to antibiotics existing in the environment is a predisposing factor for developmental malformation with metabolic disorders in offspring. In this study, female zebrafish (3 months) were exposed to 0.05 mg/L and 0.5 mg/L florfenicol (FF) for 28 days. After pairing and spawning with...

Full description

Bibliographic Details
Main Authors: Lin Zhang, Jing Qiu, Yameng Li, Linjuan He, Mingcai Mao, Tiancai Wang, Yecan Pan, Zishu Li, Xiyan Mu, Yongzhong Qian
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Florfenicol
Offspring
Development toxicity
Metabolism
Mitochondria
Reactive oxygen species
Online Access:http://www.sciencedirect.com/science/article/pii/S014765132300101X

Internet

http://www.sciencedirect.com/science/article/pii/S014765132300101X

Similar Items