Peptides of Matrix Gla protein inhibit nucleation and growth of hydroxyapatite and calcium oxalate monohydrate crystals.

Matrix Gla protein (MGP) is a phosphorylated and γ-carboxylated protein that has been shown to prevent the deposition of hydroxyapatite crystals in the walls of blood vessels. MGP is also expressed in kidney and may inhibit the formation of kidney stones, which mainly consist of another crystalline...

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Bibliographic Details
Main Authors: Maria Goiko, Joshua Dierolf, Jared S Gleberzon, Yinyin Liao, Bernd Grohe, Harvey A Goldberg, John R de Bruyn, Graeme K Hunter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3827180?pdf=render