Non-invasive Metabolomic Profiling of Embryo Culture Medium Using Raman Spectroscopy With Deep Learning Model Predicts the Blastocyst Development Potential of Embryos

Non-invasive Metabolomic Profiling of Embryo Culture Medium Using Raman Spectroscopy With Deep Learning Model Predicts the Blastocyst Development Potential of Embryos

Purpose: This study aimed to establish a non-invasive predicting model via Raman spectroscopy for evaluating the blastocyst development potential of day 3 high-quality cleavage stage embryos.Methods: Raman spectroscopy was used to detect the metabolic spectrum of spent day 3 (D3) embryo culture medi...

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Bibliographic Details
Main Authors: Wei Zheng, Shuoping Zhang, Yifan Gu, Fei Gong, Lingyin Kong, Guangxiu Lu, Ge Lin, Bo Liang, Liang Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Physiology
Subjects:
embryo viability prediction
metabolomic profiling
multilayer perceptron
non-invasive assessment
Raman spectroscopy
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.777259/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.777259/full

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