Reduction in Interferon-Stimulated Genes Contributes to High-Yield Production of Influenza Virus in Suspension MDCK Cells

Reduction in Interferon-Stimulated Genes Contributes to High-Yield Production of Influenza Virus in Suspension MDCK Cells

Compared with the traditional vaccine produced in embryonated chicken eggs, cell-based manufacturing represented by the Madin–Darby canine kidney (MDCK) cell line has a larger production scale and reduces the risk of egg shortage in a pandemic. Establishing a culture system that enables high product...

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Bibliographic Details
Main Authors: Qi Wang, Jian Luo, Beibei Li, Qian Ye, Wenting Xu, Feixia Gao, Linting Zhou, Wenyue Lu, Wen-Song Tan, Xiuling Li
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Vaccines
Subjects:
influenza virus
suspension MDCK cells
vaccines
interferon-stimulated genes
high-yield production
Online Access:https://www.mdpi.com/2076-393X/12/3/287

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https://www.mdpi.com/2076-393X/12/3/287

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