Metabolic modelling-based in silico drug target prediction identifies six novel repurposable drugs for melanoma

Metabolic modelling-based in silico drug target prediction identifies six novel repurposable drugs for melanoma

Abstract Despite high initial response rates to targeted kinase inhibitors, the majority of patients suffering from metastatic melanoma present with high relapse rates, demanding for alternative therapeutic options. We have previously developed a drug repurposing workflow to identify metabolic drug...

Full description

Bibliographic Details
Main Authors: Tamara Bintener, Maria Pires Pacheco, Demetra Philippidou, Christiane Margue, Ali Kishk, Greta Del Mistro, Luca Di Leo, Maria Moscardó Garcia, Rashi Halder, Lasse Sinkkonen, Daniela De Zio, Stephanie Kreis, Dagmar Kulms, Thomas Sauter
Format: Article
Language:English
Published: Nature Publishing Group 2023-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-05955-1

Internet

https://doi.org/10.1038/s41419-023-05955-1

Similar Items