Expanding the Chemical Space of Arsenicin A-C Related Polyarsenicals and Evaluation of Some Analogs as Inhibitors of Glioblastoma Stem Cell Growth

Expanding the Chemical Space of Arsenicin A-C Related Polyarsenicals and Evaluation of Some Analogs as Inhibitors of Glioblastoma Stem Cell Growth

The marine polyarsenical metabolite arsenicin A is the landmark of a series of natural and synthetic molecules characterized by an adamantane-like tetraarsenic cage. Arsenicin A and related polyarsenicals have been evaluated for their antitumor effects in vitro and have been proven more potent than...

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Bibliographic Details
Main Authors: Jacopo Vigna, Denise Sighel, Emanuele Filiberto Rosatti, Andrea Defant, Michael Pancher, Viktoryia Sidarovich, Alessandro Quattrone, Ines Mancini
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Marine Drugs
Subjects:
marine metabolite
polyarsenical
As-S cage
calculated NMR spectrum
arsenic trioxide
antitumor
Online Access:https://www.mdpi.com/1660-3397/21/3/186

Internet

https://www.mdpi.com/1660-3397/21/3/186

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