Long-Term Protection Elicited by an Inactivated Vaccine Supplemented with a Water-Based Adjuvant against Infectious Hematopoietic Necrosis Virus in Rainbow Trout (Oncorhynchus mykiss)

ABSTRACT Previous inactivated vaccines against infectious hematopoietic necrosis (IHN) usually had a strong early immune protective effect but failed to provide long-term protection in rainbow trout (Oncorhynchus mykiss). To find a method for stabilizing the desired protective effect of IHN vaccines...

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Bibliographic Details
Main Authors: Yujie Lin, Guangming Ren, Jingzhuang Zhao, Yizhi Shao, Baoquan He, Xin Tang, Ou Sha, Wenwen Zhao, Qi Liu, Liming Xu, Tongyan Lu
Format: Article
Language:English
Published: American Society for Microbiology 2022-12-01
Series:Microbiology Spectrum
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03245-22