RUVBL1 accelerates tongue squamous cell carcinoma by mediating CRaf/MEK/ERK pathway

Summary: RAF/MEK/ERK pathway is frequently activated in tumor. Therefore, this study will investigate the function of RUVBL1 (RAF-binding protein) in tongue squamous cell carcinoma (TSCC). Bioinformatics was performed to identify differentially expressed mRNAs (DE-mRNAs) in TCGA-oral squamous cell c...

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Bibliographic Details
Main Authors: Xin-yu Zhang, Yang Liu, Qiong Rong, Ming-yue Qi, Hui Guo
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224006552