Micro-simulation insights into the functional and mechanistic understanding of glycyrrhizin against asthma

Asthma is a common chronic respiratory disease, which causes inflammation and airway stenosis, leading to dyspnea, wheezing and chest tightness. Using transgelin-2 as a target, we virtually screened the lead compound glycyrrhizin from the self-built database of anti-asthma compounds by molecular doc...

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Bibliographic Details
Main Authors: Jian-Hong Qi, Dong-Chuan Xu, Xiao-Long Wang, Ding-Yuan Cai, Yi Wang, Wei Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1220368/full