Sequence-specific dimerization of a transmembrane helix in amphipol A8-35.

As traditional detergents might destabilize or even denature membrane proteins, amphiphilic polymers have moved into the focus of membrane-protein research in recent years. Thus far, Amphipols are the best studied amphiphilic copolymers, having a hydrophilic backbone with short hydrophobic chains. H...

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Bibliographic Details
Main Authors: Michael Stangl, Sebastian Unger, Sandro Keller, Dirk Schneider
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0110970