Elongation factor 2 in cancer: a promising therapeutic target in protein translation
Abstract Aberrant elongation of proteins can lead to the activation of oncogenic signaling pathways, resulting in the dysregulation of oncogenic signaling pathways. Eukaryotic elongation factor 2 (eEF2) is an essential regulator of protein synthesis that precisely elongates nascent peptides in the p...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-12-01
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Series: | Cellular & Molecular Biology Letters |
Subjects: | |
Online Access: | https://doi.org/10.1186/s11658-024-00674-7 |