The potential role of m6A modifications on immune cells and immunotherapy

The potential role of m6A modifications on immune cells and immunotherapy

N6-methyladenosine (m6A), is the most prevalent and reversible post-transcriptional epigenetic modification of RNA in mammals. Dysregulation of m6A modifications impacts RNA procession, degradation, translocation, and translation, disrupting immune cell homeostasis and promoting tumor initiation and...

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Bibliographic Details
Main Authors: Linchuan Gan, Yuxiang Zhao, Yajuan Fu, Qi Chen
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Biomedicine & Pharmacotherapy
Subjects:
N6-methyladenosine (m6A)
Immune cells
Tumor microenvironment
Immunotherapy
Immune homeostasis
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223001312

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http://www.sciencedirect.com/science/article/pii/S0753332223001312

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