Tumor cells positive and negative for the common cancer stem cell markers are capable of initiating tumor growth and generating both progenies.

Tumor cells positive and negative for the common cancer stem cell markers are capable of initiating tumor growth and generating both progenies.

The cancer stem cell (CSC) model depicts that tumors are hierarchically organized and maintained by CSCs lying at the apex. CSCs have been "identified" in a variety of tumors through the tumor-forming assay, in which tumor cells distinguished by a certain cell surface marker (known as a CS...

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Bibliographic Details
Main Authors: Sheng-Dong Huang, Yang Yuan, Hao Tang, Xiao-Hong Liu, Chuan-Gang Fu, He-Zhong Cheng, Jian-Wei Bi, Yong-Wei Yu, De-Jun Gong, Wei Zhang, Jie Chen, Zhi-Yun Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3549952?pdf=render

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http://europepmc.org/articles/PMC3549952?pdf=render

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