Developmental regulation of protein O-GlcNAcylation, O-GlcNAc transferase, and O-GlcNAcase in mammalian brain.

Developmental regulation of protein O-GlcNAcylation, O-GlcNAc transferase, and O-GlcNAcase in mammalian brain.

O-GlcNAcylation is a common posttranslational modification of nucleocytoplasmic proteins by β-N-acetylglucosamine (GlcNAc). The dynamic addition and removal of O-GlcNAc groups to and from proteins are catalyzed by O-linked N-acetylglucosamine transferase (O-GlcNAc transferase, OGT) and β-N-acetylglu...

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Bibliographic Details
Main Authors: Ying Liu, Xiaojing Li, Yang Yu, Jianhua Shi, Zhihou Liang, Xiaoqin Run, Yi Li, Chun-ling Dai, Inge Grundke-Iqbal, Khalid Iqbal, Fei Liu, Cheng-Xin Gong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3425547?pdf=render

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http://europepmc.org/articles/PMC3425547?pdf=render

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