A positive feed-forward loop between Fusobacterium nucleatum and ethanol metabolism reprogramming drives laryngeal cancer progression and metastasis

Summary: Alcohol consumption, which affects the structure and composition of the laryngeal microbiota, is one of the most important risk factors for laryngeal squamous cell cancer (LSCC). Our results demonstrated that high enrichment of Fusobacterium nucleatum (F. nucleatum) in LSCC was associated w...

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Bibliographic Details
Main Authors: Chi-Yao Hsueh, Qiang Huang, Hongli Gong, Yujie Shen, Ji Sun, Hui-Ching Lau, Duo Zhang, Di Tang, Chunping Wu, Yang Guo, Huiying Huang, Pengyu Cao, Lei Tao, Ming Zhang, Liang Zhou
Format: Article
Language:English
Published: Elsevier 2022-02-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222000992