A Supercluster of Neutralizing Epitopes at the Interface of Ricin’s Enzymatic (RTA) and Binding (RTB) Subunits

As part of an effort to engineer ricin antitoxins and immunotherapies, we previously produced and characterized a collection of phage-displayed, heavy chain-only antibodies (VHHs) from alpacas that had been immunized with ricin antigens. In our initial screens, we identified nine VHHs directed again...

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Bibliographic Details
Main Authors: Amanda Y. Poon, David J. Vance, Yinghui Rong, Dylan Ehrbar, Nicholas J. Mantis
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/9/12/378