Metastable DNA methylation sites associated with longitudinal lung function decline and aging in humans: an epigenome-wide study in the NAS and KORA cohorts

Metastable DNA methylation sites associated with longitudinal lung function decline and aging in humans: an epigenome-wide study in the NAS and KORA cohorts

DNA methylation is an epigenetic regulator of gene transcription, which has been found to be both metastable and variable within human cohort studies. Currently, few studies have been done to identify metastable DNA methylation biomarkers associated with longitudinal lung function decline in humans....

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Bibliographic Details
Main Authors: Juan Jose Carmona, Richard T. Barfield, Tommaso Panni, Jamaji C. Nwanaji-Enwerem, Allan C. Just, John N. Hutchinson, Elena Colicino, Stefan Karrasch, Simone Wahl, Sonja Kunze, Nadereh Jafari, Yinan Zheng, Lifang Hou, Dawn L. DeMeo, Augusto A. Litonjua, Pantel S. Vokonas, Annette Peters, Xihong Lin, Joel Schwartz, Holger Schulz, Andrea A. Baccarelli
Format: Article
Language:English
Published: Taylor & Francis Group 2018-11-01
Series:Epigenetics
Subjects:
biomarker
dna methylation
pulmonary function
lung function decline
Online Access:http://dx.doi.org/10.1080/15592294.2018.1529849

Internet

http://dx.doi.org/10.1080/15592294.2018.1529849

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