Distinct roles of the IRE1α arm and PERK arm of unfolded protein response in arachidonic acid-induced ferroptosis in hepatocytes

Distinct roles of the IRE1α arm and PERK arm of unfolded protein response in arachidonic acid-induced ferroptosis in hepatocytes

Ferroptosis is a distinct form of cell death that is driven by iron-dependent phospholipid peroxidation. Polyunsaturated fatty acids (PUFAs), particularly arachidonic acid (AA) and adrenal acid (AdA), are most prone to lipid peroxidation, which induces ferroptosis and affects the function of cell me...

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Bibliographic Details
Main Authors: Han Zhang, Kai Han, Shutao Yin, Lihong Fan, Hongbo Hu, Chong Zhao
Format: Article
Language:English
Published: Maximum Academic Press 2023-07-01
Series:Food Innovation and Advances
Subjects:
hepatocyte
er stress
ferroptosis
ferritinophagy
polyunsaturated fatty
Online Access:https://www.maxapress.com/article/doi/10.48130/FIA-2023-0020

Internet

https://www.maxapress.com/article/doi/10.48130/FIA-2023-0020

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