Microsomal glutathione transferase 1 controls metastasis and therapeutic response in melanoma

Microsomal glutathione transferase 1 controls metastasis and therapeutic response in melanoma

While recent targeted and immunotherapies in malignant melanoma are encouraging, most patients acquire resistance, implicating a need to identify additional drug targets to improve outcomes. Recently, attention has been given to pathways that regulate redox homeostasis, especially the lipid peroxida...

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Bibliographic Details
Main Authors: Jie Zhang, Zhi-wei Ye, Paramita Chakraborty, Zhenwu Luo, John Culpepper, Muhammad Aslam, Leilei Zhang, Katarina Johansson, Jesper Z. Haeggström, Jianqiang Xu, Magnus Olsson, Danyelle M. Townsend, Shikhar Mehrotra, Ralf Morgenstern, Kenneth D. Tew
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Pharmacological Research
Subjects:
Microsomal glutathione transferase 1
Melanoma
Ferroptosis
Oxidative stress
Redox
Metastasis
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661823002554

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http://www.sciencedirect.com/science/article/pii/S1043661823002554

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