Engrafted glial progenitor cells yield long-term integration and sensory improvement in aged mice

Engrafted glial progenitor cells yield long-term integration and sensory improvement in aged mice

Abstract Aging causes astrocyte morphological degeneration and functional deficiency, which impairs neuronal functions. Until now, whether age-induced neuronal deficiency could be alleviated by engraftment of glial progenitor cell (GPC) derived astrocytes remained unknown. In the current study, GPCs...

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Bibliographic Details
Main Authors: Zhiqi Yang, Mingyue Gong, Tingliang Jian, Jin Li, Chuanyan Yang, Qinlong Ma, Ping Deng, Yuxia Wang, Mingzhu Huang, Haoyu Wang, Shaofan Yang, Xiaowei Chen, Zhengping Yu, Manxia Wang, Chunhai Chen, Kuan Zhang
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Stem Cell Research & Therapy
Subjects:
Glial progenitor cells
Transplantation
Endfeet
Aquaporin-4
Sensory response
Aging
Online Access:https://doi.org/10.1186/s13287-022-02959-0

Internet

https://doi.org/10.1186/s13287-022-02959-0

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