High glucose enhances the activation of NLRP3 inflammasome by ambient fine particulate matter in alveolar macrophages

Abstract Background Epidemiological studies have demonstrated that individuals with preexisting conditions, including diabetes mellitus (DM), are more susceptible to air pollution. However, the underlying mechanisms remain unclear. In this study, we proposed that a high glucose setting enhances ambi...

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Bibliographic Details
Main Authors: Yiqun Mo, Luke Mo, Yue Zhang, Yuanbao Zhang, Jiali Yuan, Qunwei Zhang
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Particle and Fibre Toxicology
Subjects:
Online Access:https://doi.org/10.1186/s12989-023-00552-8