An in vitro model to explore subchondral perfusion and intraosseous pressure

Abstract Background Little is known about subchondral perfusion physiology. We developed a 3Rs (Replace, Reduce, Refine) compliant in vitro calf foot model to explore perfusion and intraosseous pressure (IOP). Methods Calf feet were catheterised and perfused with serum. IOP was measured at three sit...

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Príomhchruthaitheoirí: Michael Beverly, David Murray
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: Wiley 2019-08-01
Sraith:Journal of Experimental Orthopaedics
Ábhair:
Rochtain ar líne:http://link.springer.com/article/10.1186/s40634-019-0207-3