An in vitro model to explore subchondral perfusion and intraosseous pressure
Abstract Background Little is known about subchondral perfusion physiology. We developed a 3Rs (Replace, Reduce, Refine) compliant in vitro calf foot model to explore perfusion and intraosseous pressure (IOP). Methods Calf feet were catheterised and perfused with serum. IOP was measured at three sit...
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| פורמט: | Article |
| שפה: | English |
| יצא לאור: |
Wiley
2019-08-01
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| סדרה: | Journal of Experimental Orthopaedics |
| נושאים: | |
| גישה מקוונת: | http://link.springer.com/article/10.1186/s40634-019-0207-3 |