Loss of SQSTM1/p62 Induces Obesity and Exacerbates Alcohol-Induced Liver Injury in Aged MiceSummary

Loss of SQSTM1/p62 Induces Obesity and Exacerbates Alcohol-Induced Liver Injury in Aged MiceSummary

Background: Alcohol-associated liver disease (ALD) is a worldwide health problem, of which the effective treatment is still lacking. Both detrimental and protective roles of adipose tissue have been implicated in ALD. Although alcohol increases adipose tissue lipolysis to promote alcohol-induced liv...

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Bibliographic Details
Main Authors: Hui Qian, Xiaojuan Chao, Shaogui Wang, Yuan Li, Xiaoxiao Jiang, Zhaoli Sun, Thomas Rülicke, Kurt Zatloukal, Hong-Min Ni, Wen-Xing Ding
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Adipose Tissue
Adipokine
ALD
Autophagy
Steatosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X2300019X

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http://www.sciencedirect.com/science/article/pii/S2352345X2300019X

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