Size does matter: an integrative in vivo-in silico approach for the treatment of critical size bone defects.

Although bone has a unique restorative capacity, i.e., it has the potential to heal scarlessly, the conditions for spontaneous bone healing are not always present, leading to a delayed union or a non-union. In this work, we use an integrative in vivo-in silico approach to investigate the occurrence...

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Bibliographic Details
Main Authors: Aurélie Carlier, Nick van Gastel, Liesbet Geris, Geert Carmeliet, Hans Van Oosterwyck
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-11-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1003888&type=printable