How fibrosis influences imaging and surgical decisions in pancreatic cancer

How fibrosis influences imaging and surgical decisions in pancreatic cancer

Our understanding of pancreatic ductal adenocarcinoma is shifting away from a disease of malignant ductal cells-only, towards a complex system where tumor evolution is a result of interaction of cancer cells with their microenvironment. This change has led to intensification of research focusing on...

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Bibliographic Details
Main Authors: Mert eErkan, Simone eHausmann, Christoph W Michalski, Melissa eSchlitter, Alexander A Fingerle, Martin eDobritz, Helmut eFriess, Jörg eKleeff
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-10-01
Series:Frontiers in Physiology
Subjects:
Angiogenesis
stellate cells
microenvironment
Molecular diagnostics
desmoplasia
periostin
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00389/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00389/full

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