An AAV vector-mediated gene delivery approach facilitates reconstitution of functional human CD8+ T cells in mice.
In the present study, a novel adeno-associated virus (AAV) vector-mediated gene delivery approach was taken to improve the reconstitution of functional CD8(+) T cells in humanized mice, thereby mimicking the human immune system (HIS). Human genes encoding HLA-A2 and selected human cytokines (A2/hucy...
| Những tác giả chính: | , , , , |
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| Định dạng: | Bài viết |
| Ngôn ngữ: | English |
| Được phát hành: |
Public Library of Science (PLoS)
2014-01-01
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| Loạt: | PLoS ONE |
| Truy cập trực tuyến: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0088205&type=printable |